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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LIPE All Species: 2.73
Human Site: S240 Identified Species: 8.57
UniProt: Q05469 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05469 NP_005348.2 1076 116598 S240 E S E S D V G S S S D T D S P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533655 889 96890 A101 V A Q G M K L A S K G K H E V
Cat Felis silvestris
Mouse Mus musculus P54310 759 83329
Rat Rattus norvegicus P15304 1068 116793 S239 D M E K Y L N S S S K S N P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001124413 832 91875 G45 R I Q E Q T R G I E P A L R A
Zebra Danio Brachydanio rerio XP_686139 538 59103
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397143 733 81786
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194738 827 91195 E40 Q L I I N N I E Y F Q K L R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 66.6 N.A. 60.3 71.9 N.A. N.A. N.A. 44.3 33.7 N.A. N.A. 26 N.A. 32.1
Protein Similarity: 100 N.A. N.A. 72.6 N.A. 64.5 79.6 N.A. N.A. N.A. 55.1 43 N.A. N.A. 40.7 N.A. 46.7
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 0 33.3 N.A. N.A. N.A. 0 0 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 N.A. N.A. 26.6 N.A. 0 60 N.A. N.A. N.A. 6.6 0 N.A. N.A. 0 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 13 0 0 0 0 0 13 0 0 0 13 0 0 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 0 0 13 0 0 0 0 0 13 0 13 0 0 % D
% Glu: 13 0 25 13 0 0 0 13 0 13 0 0 0 13 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % F
% Gly: 0 0 0 13 0 0 13 13 0 0 13 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % H
% Ile: 0 13 13 13 0 0 13 0 13 0 0 0 0 0 0 % I
% Lys: 0 0 0 13 0 13 0 0 0 13 13 25 0 0 0 % K
% Leu: 0 13 0 0 0 13 13 0 0 0 0 0 25 0 0 % L
% Met: 0 13 0 0 13 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 13 13 13 0 0 0 0 0 13 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 13 0 0 13 25 % P
% Gln: 13 0 25 0 13 0 0 0 0 0 13 0 0 0 0 % Q
% Arg: 13 0 0 0 0 0 13 0 0 0 0 0 0 25 0 % R
% Ser: 0 13 0 13 0 0 0 25 38 25 0 13 0 13 13 % S
% Thr: 0 0 0 0 0 13 0 0 0 0 0 13 0 0 0 % T
% Val: 13 0 0 0 0 13 0 0 0 0 0 0 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 13 0 0 0 13 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _